British Museum blog

New evidence of human cancer found at ancient Amara West

scan of human bone

Michaela Binder, Durham University and Neal Spencer, British Museum

Cancer is one of the world’s most common causes of death today, but there is little evidence from before industrialisation: almost nothing is known about the history of the disease in the past. We generally assume cancer is strongly related to modern lifestyle and environment. But the analysis of skeletal and mummified human remains recovered during archaeological excavations can provide insights into such diseases in the distant past.

Until now, only a small number of skeletons with evidence for cancer have been identified. While the oldest primary bone cancer is around 6,000 years old, the earliest example of bone metastases related to a soft tissue cancer dates to around 3000 BC. However, because only the skull is preserved, there are doubts about the accuracy of the diagnosis. Only nine more individuals with – often tentative – evidence of cancer predate the first millennium AD. The majority of these individuals come from Ancient Egypt. This is perhaps mainly because the long history of archaeological research has resulted in a very large amount of skeletal and mummified human remains becoming available for study. They are very well preserved and have received a great deal of attention from medical doctors and physical anthropologists since the 19th century.

View southwest over Amara West town, on the Nile river. Photo: Susie Green.

View southwest over Amara West town, on the Nile river. Photo: Susie Green.

In February 2013, the skeleton of a man who died between the age of 20 and 35 years was excavated in a tomb at Amara West, in northern Sudan. Founded around 1300 BC in the reign of Seti I, the town was designed as a new centre of the Egyptian control of Upper Nubia (Kush). The British Museum has been working at the site since 2008. Excavations in the town allow us glimpses of ancient lives: how houses were refurbished, what people ate, religious and ritual practices, where rubbish was disposed – and how the town changed over two centuries of occupation. Bioarchaeological work in the cemeteries is providing further insights into the ancient inhabitants: their life expectancy, diet and health.

The underground chamber tomb where skeleton 244-8 was buried

The underground chamber tomb where skeleton 244-8 was buried

Skeleton 244-8. The scarab (inset) was placed in the man's hands.

Skeleton 244-8. The scarab (inset) was placed in the man’s hands.

This individual (skeleton 244-8) was buried in a large underground chamber tomb (G244), perhaps used for a family around 1200 BC. The body was placed in a painted wooden coffin, with an Egyptian-style scaraboid placed in the hands. The bones of the torso, upper arms and upper legs have a large number of holes, 5-25mm in diameter. Radiographic examination of the bones revealed the holes are even larger beneath the bone surface. These holes were caused by metastatic carcinoma spreading from a soft tissue cancer: the oldest complete skeleton of a metastatic cancer found, anywhere, to date. The study, jointly conducted by researchers at the British Museum and Durham University is being published in the Public Library of Science journal PLOS One.

Small holes in the breast bone (arrows). The radiographic image shows enlargement and additional holes underneath the surface.

Small holes in the breast bone (arrows). The radiographic image shows enlargement and additional holes underneath the surface.

What caused such a case of cancer? Schistosomiasis, a parasitic disease which was and still is a major health problem in the Nile valley, can cause breast cancer in men. Smoke from woodfires within houses continues to be a problem in modern Sudan. At Amara West, most of the small houses were provided with cylindrical bread ovens, often three side-by-side in a small room. Careful excavation has revealed that many of these oven rooms were roofed: these would have quickly filled up with smoke, exposing people to potentially harmful substances.

Small room in house E13.4, originally roofed, with three bread ovens

Small room in house E13.4, originally roofed, with three bread ovens

Understanding the evolution, history and factors that could have caused cancer prior to the onset of modern living conditions is important not only for archaeology but even more so for medical research. Skeletal human remains, set within a well-documented historical, archaeological and environmental context are a key element for any such attempts. This may in future be crucial to develop new research strategies and therapies in order to tackle what has become the world’s deadliest disease.

The identification of such cases, and other diseases, among the population of towns such as Amara West, provides a more direct sense of ancient experience than those provided by ancient texts, architectural remains or the objects people left behind.

Follow the latest from the British Museum team now excavating at Amara West: http://blog.amarawest.britishmuseum.org/
If you would like to leave a comment click on the title

Filed under: Amara West, , , , , ,

3 Responses - Comments are closed.

  1. Reblogged this on Ace British History News 2014 and commented:
    #ABHN2014

    Like

  2. As the book of Ecclesiastes says: “Nihil novus est sub solis” – There is nothing new under the sun…

    Like

    • Form Joan, Line please. says:

      I’m sorry, Joan didn’t get to read me when I went to Britain. It’s all about Iphigenia. I suppose Iphigenia went to Britain. Read on.

      Like

Enter your email address to follow this blog and receive notifications of new posts by email.

Join 14,375 other followers

Categories

Follow @britishmuseum on Twitter

British Museum on Instagram

For our final #MuseumInstaSwap post we’re highlighting the 'Make Do and Mend' campaign of the Second World War, as told by our partner @ImperialWarMuseums in their #FashionontheRation exhibition.

The campaign was launched to encourage people to make their existing supplies of clothes last longer. Posters and leaflets were circulated with advice on subjects including how to prevent moth damage to woollens, how to make shoes last longer or how to care for different fabrics. As the war went on, buying new was severely restricted by coupon limits and no longer an option for many people. The ability to repair, renovate and make one's own clothes became increasingly important. Although shoppers would have to hand over coupons for dressmaking fabric as well as readymade clothes, making clothes was often cheaper and saved coupons. ‘Make Do and Mend’ classes took place around the country, teaching skills such as pattern cutting. Dress makers and home sewers often had to be experimental in their choice of fabrics. Despite disliking much of the official rhetoric to Make Do and Mend, many people demonstrated great creativity and adaptability in dealing with rationing. Individual style flourished. Shortages necessitated imaginative use of materials, recycling and renovating of old clothes and innovative use of home-made accessories, which could alter or smarten up an outfit. Many women used furnishing fabrics for dressmaking until these too were rationed. Blackout material, which did not need points, was also sometimes used. Parachute silk was highly prized for underwear, nightclothes and wedding dresses.

We've really enjoyed working with and learning from our friends at @imperialwarmuseums this week. You can catch up on all our posts and discover many more stories from London’s museums with #MuseumInstaSwap. © IWM (Art.IWM PST 4773 For #MuseumInstaSwap we’re discovering the street style of the Second World War in the #FashionontheRation exhibition at @ImperialWarMuseums. In this archive photo a female member of the Air Raid Precautions staff applies her lipstick between emergency calls.

In wartime Britain it was unfashionable to be seen wearing clothes that were obviously showy, yet women were frequently implored not to let 'standards' slip too far. There was genuine concern that a lack of interest in personal appearance could be a sign of low morale, which could have a detrimental impact on the war effort. The government's concern for the morale of women was a major factor in the decision to continue the manufacture of cosmetics, though in much reduced quantities. Make-up was never rationed, but was subject to a luxury tax and was very expensive. Many cosmetics firms switched some of their production to items needed for the war effort. Coty, for example, were known for their face powder and perfumes but also made army foot powder and anti-gas ointment. Make-up and hair styles took on an increased importance and many women went to great lengths to still feel well-dressed and stylish even if their clothes were last season's, their stockings darned and accessories home-made. As with clothing, women found creative ways around shortages, with beetroot juice used for a splash of lip colour and boot polish passing for mascara.

Discover more stories from London’s museums with #MuseumInstaSwap © IWM (D 176) In the @ImperialWarMuseums exhibition ‘Fashion on the Ration: 1940s street style’ we can see how men and women found new ways to dress while clothing was rationed. Displays of original clothes from the era, from military uniforms to utility underwear, reveal what life was really like on the home front in wartime Britain.

Despite the limitations imposed by rationing, clothing retailers sought to retain and even expand their customer base during the Second World War. Britain's high street adapted in response to wartime conditions, and this was reflected in their retail ranges. The government intervened in the mass manufacture of high street fashions with the arrival of the Utility clothing scheme in 1942. Shoppers carefully spent their precious clothing coupons and money on new clothes to make sure their purchases would be suitable across spring, summer and autumn and winter. Despite the restrictions, the war and civilian austerity did not put an end to creative design, commercial opportunism or fashionable trends on the British home front.

#FashionontheRation exhibition runs @imperialwarmuseums until 31 August.

Discover more stories from London’s museums with #MuseumInstaSwap. For our final day of #MuseumInstaSwap we’re learning about the Second World War @ImperialWarMuseums, and discovering the impact of the war on ordinary people. 
Clothes were rationed in Britain from 1 June 1941. This limited the amount of new garments people could buy until 1949, four years after the war's end. The British government needed to reduce production and consumption of civilian clothes to safeguard raw materials and release workers and factory space for war production. As with food rationing, which had been in place since 1940, one of the reasons for introducing civilian clothes rationing was to ensure fairness. Rationing sought to ensure a more equal distribution of clothing and improve the availability of garments in the shops.

As this poster shows, the rationing scheme worked by allocating each type of clothing item a 'points' value which varied according to how much material and labour went into its manufacture. Eleven coupons were needed for a dress, two needed for a pair of stockings, and eight coupons required for a man's shirt or a pair of trousers. Women's shoes meant relinquishing five coupons, and men's footwear cost seven coupons. When buying new clothes, the shopper had to hand over coupons with a 'points' value as well as money. Every adult was initially given an allocation of 66 points to last one year, but this allocation shrank as the war progressed. © IWM (Art.IWM PST 8293) This week on @instagram we’ve joined up with other London museums to highlight our shared stories. Our partner is @imperialwarmuseums, whose incredible collection brings people’s experiences of modern war and conflict to life. Follow #MuseumInstaSwap to discover some of the intriguing historical connections we have found, as well as insights into everyday life during wartime. As part of our #MuseumInstaSwap with @ImperialWarMuseums, we’ve been given special access to the Churchill War Rooms – located deep below the streets of Westminster.
This is Prime Minister Winston Churchill’s bedroom, which includes his private desk, briefcase and papers, his bed and chamber pot and even an original cigar! The bedroom is located close to the Map Room, keeping Churchill as close as possible to the epicentre of Cabinet War Rooms.
Following the surrender of the Japanese Forces the doors to the War Rooms were locked on 16 August 1945 and the complex was left undisturbed until Parliament ensured its preservation as a historic site in 1948. Knowledge of the site and access to it remained highly restricted until the late 1970s when @ImperialWarMuseums began the task of preserving the site and its contents, making them accessible to as wide an audience as possible and opening them to the public in 1984.
Discover more stories from London’s museums with #MuseumInstaSwap
Follow

Get every new post delivered to your Inbox.

Join 14,375 other followers

%d bloggers like this: