British Museum blog

New evidence of human cancer found at ancient Amara West

scan of human bone

Michaela Binder, Durham University and Neal Spencer, British Museum

Cancer is one of the world’s most common causes of death today, but there is little evidence from before industrialisation: almost nothing is known about the history of the disease in the past. We generally assume cancer is strongly related to modern lifestyle and environment. But the analysis of skeletal and mummified human remains recovered during archaeological excavations can provide insights into such diseases in the distant past.

Until now, only a small number of skeletons with evidence for cancer have been identified. While the oldest primary bone cancer is around 6,000 years old, the earliest example of bone metastases related to a soft tissue cancer dates to around 3000 BC. However, because only the skull is preserved, there are doubts about the accuracy of the diagnosis. Only nine more individuals with – often tentative – evidence of cancer predate the first millennium AD. The majority of these individuals come from Ancient Egypt. This is perhaps mainly because the long history of archaeological research has resulted in a very large amount of skeletal and mummified human remains becoming available for study. They are very well preserved and have received a great deal of attention from medical doctors and physical anthropologists since the 19th century.

View southwest over Amara West town, on the Nile river. Photo: Susie Green.

View southwest over Amara West town, on the Nile river. Photo: Susie Green.

In February 2013, the skeleton of a man who died between the age of 20 and 35 years was excavated in a tomb at Amara West, in northern Sudan. Founded around 1300 BC in the reign of Seti I, the town was designed as a new centre of the Egyptian control of Upper Nubia (Kush). The British Museum has been working at the site since 2008. Excavations in the town allow us glimpses of ancient lives: how houses were refurbished, what people ate, religious and ritual practices, where rubbish was disposed – and how the town changed over two centuries of occupation. Bioarchaeological work in the cemeteries is providing further insights into the ancient inhabitants: their life expectancy, diet and health.

The underground chamber tomb where skeleton 244-8 was buried

The underground chamber tomb where skeleton 244-8 was buried

Skeleton 244-8. The scarab (inset) was placed in the man's hands.

Skeleton 244-8. The scarab (inset) was placed in the man’s hands.

This individual (skeleton 244-8) was buried in a large underground chamber tomb (G244), perhaps used for a family around 1200 BC. The body was placed in a painted wooden coffin, with an Egyptian-style scaraboid placed in the hands. The bones of the torso, upper arms and upper legs have a large number of holes, 5-25mm in diameter. Radiographic examination of the bones revealed the holes are even larger beneath the bone surface. These holes were caused by metastatic carcinoma spreading from a soft tissue cancer: the oldest complete skeleton of a metastatic cancer found, anywhere, to date. The study, jointly conducted by researchers at the British Museum and Durham University is being published in the Public Library of Science journal PLOS One.

Small holes in the breast bone (arrows). The radiographic image shows enlargement and additional holes underneath the surface.

Small holes in the breast bone (arrows). The radiographic image shows enlargement and additional holes underneath the surface.

What caused such a case of cancer? Schistosomiasis, a parasitic disease which was and still is a major health problem in the Nile valley, can cause breast cancer in men. Smoke from woodfires within houses continues to be a problem in modern Sudan. At Amara West, most of the small houses were provided with cylindrical bread ovens, often three side-by-side in a small room. Careful excavation has revealed that many of these oven rooms were roofed: these would have quickly filled up with smoke, exposing people to potentially harmful substances.

Small room in house E13.4, originally roofed, with three bread ovens

Small room in house E13.4, originally roofed, with three bread ovens

Understanding the evolution, history and factors that could have caused cancer prior to the onset of modern living conditions is important not only for archaeology but even more so for medical research. Skeletal human remains, set within a well-documented historical, archaeological and environmental context are a key element for any such attempts. This may in future be crucial to develop new research strategies and therapies in order to tackle what has become the world’s deadliest disease.

The identification of such cases, and other diseases, among the population of towns such as Amara West, provides a more direct sense of ancient experience than those provided by ancient texts, architectural remains or the objects people left behind.

Follow the latest from the British Museum team now excavating at Amara West: http://blog.amarawest.britishmuseum.org/
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3 Responses - Comments are closed.

  1. Reblogged this on Ace British History News 2014 and commented:
    #ABHN2014

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  2. As the book of Ecclesiastes says: “Nihil novus est sub solis” – There is nothing new under the sun…

    Like

    • Form Joan, Line please. says:

      I’m sorry, Joan didn’t get to read me when I went to Britain. It’s all about Iphigenia. I suppose Iphigenia went to Britain. Read on.

      Like

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Our #AfricanRockArt project team is cataloguing and uploading around 25,000 digital images of rock art from throughout the continent. Working with digital photographs has allowed the Museum to use new technologies to study, preserve, and enhance the rock art, while leaving it in situ.

As part of the cataloguing process, the project team document each photograph, identifying what is depicted. Sometimes images are faded or unclear. Using photo manipulation software, images can be run through a process that enhances the pigments. By focusing on different sets of colours, we can now see the layers that were previously hidden to the naked eye.

This painted panel, from Kondoa District in #Tanzania, shows the white outline of an elephant’s head at the right, along with some figures in red that it is possible to highlight with digital enhancement.

Tanzania contains some of the densest concentrations of rock art in East Africa, mainly paintings found in the Kondoa area and adjoining Lake Eyasi basin. The oldest of these paintings are attributed to hunter-gatherers and may be 10,000 years old.

Follow the link in our bio to learn more about the project and see stunning #rockart from Africa. This week we’re highlighting the work of our #AfricanRockArt image project. The project team are now in the third year of cataloguing, and have uploaded around 19,000 digital photographs of rock art from all over #Africa to the Museum’s collection online database.

This photograph shows an engraving of a large, almost life-sized elephant, found on the Messak Plateau in #Libya. This region is home to tens of thousands of depictions, and is best known for larger-than-life-size engravings of animals such as elephants, rhino and a now extinct species of buffalo. This work of rock art most likely comes from the Early Hunter Period and could be up to 12,000 years old.

Follow the link in our bio and explore 30,000 years of stunning rock art from Africa. © TARA/David Coulson. Watch the incredible discovery of this colossal statue, submerged under the sea of thousands of years. This colossal 5.4-metre statue of Hapy was discovered underwater in what was the thriving and cosmopolitan seaport of Thonis-Heracleion. It once stood in front of a temple and would have been an impressive sight for traders and visitors arriving from the Mediterranean.

Come face to face with the ancient Egyptian god Hapy for yourself in our‪ #SunkenCities exhibition, until 27 November 2016.

Colossal statue of Hapy. Thonis-Heracleion, Egypt. About 380-250 BC. Maritime Museum, Alexandria. © Franck Goddio/Hilti Foundation. The discovery of this stela, which once stood at the entrance of the main entry port into ancient Egypt, was an extraordinary moment. Its inscription detailing taxes helped solve a 2,000-year-old mystery!

This magnificent monument was crucial to revealing that Thonis (in Egyptian) and Heracleion (in Greek) were in fact the same city. The decree was issued by the pharaoh Nectanebo I, regarding the taxation of goods passing through the cities of Thonis and Naukratis, and it originally stood in the Temple of Amun-Gereb. The inscription states that this slab stood at the mouth of the ‘Sea of the Greeks’ (the Mediterranean) in Thonis.

A bilingual decree found in 1881 refers in its Greek inscription to ‘the Temple of Heracleion’ and in hieroglyphs to ‘the Temple of Amun-Gereb’. Together these objects revealed that Thonis and Heracleion were the same place.

Learn more about the deep connections between the great ancient civilisations of Egypt and Greece in our #SunkenCities exhibition.
Stela commissioned by Nectanebo I (r. 380–362 BC), Thonis-Heracleion, Egypt, 380 BC. © Franck Goddio/Hilti Foundation. For centuries nobody suspected that the #SunkenCities of Thonis-Heracleion and Canopus lay beneath the sea. Recorded in ancient writings and Greek mythology, the ancient Egyptian cities were believed to be lost.

Over the last 20 years, world-renowned archaeologist Franck Goddio and his team have excavated spectacular underwater discoveries using the latest technologies. The amazing rediscovery of these lost cities is transforming our understanding of the deep connections between the great ancient civilisations of Egypt and Greece.

See more magical moments of discovery in our #SunkenCities exhibition, until 27 November 2016. © Franck Goddio/Hilti Foundation.

#archaeology #diving #ancientEgypt This week we’re highlighting some of the incredible clocks and watches on display in the Museum. Mechanical clocks first appeared in Europe at some time between 1200 and 1300. Their introduction coincided with a growing need to regulate the times of Christian prayer in the monasteries. Telling the time with a sundial was especially difficult in western Europe with its unreliable weather. From the end of the 13th century, clocks were being installed in cathedrals, abbeys and churches all around Europe.

The design of turret clocks (public clocks) changed little over the following three centuries and this particular example, made around 1600, has similar characteristics to clocks made for churches in the medieval period. The maker of this clock was Leonard Tenant, one of the most prolific makers of church clocks in the first half of the 17th century. The clock was installed in Cassiobury Park, a country house near Watford.

See this incredible clock in Rooms 38-39 
#clocks #watches #horology
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